Current & previous research grants
At LSBR we are proud of our history of funding groundbreaking research in the field of blood transfusion and related haematology disorders. This section highlights the projects we have supported in the past and showcases the diverse and innovative research that aligns with our mission.
For current research please find the monitoring form for your reports and the information on monitoring below.
Number of research projects found: 196
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The effects of Hypoxia-inducible factor 1α (Hif-1α) on the development of hemogenic endothelium, hematopoietic stem cells and the supportive microenvironment.
- Name researcher:
- Prof E. Dzierzak
- Duration:
- 4 years
- Year:
- 2011
- Amount granted:
- €463.000
- Project number:
- 1109
- Personnel:
- Prof Elaine Dzierzak, Dept. of Cell Biology, Stem Cell Institute, Erasmus Medical Center, Rotterdam PhD student: Undine Hill, MSc (Jan. 2012 – Sept. 2012) Research technician: A.J.K. Chan (Jul. 2012 – Oct. 2012) Research technician: C.H. Gillemans (Jul. 2016 – Oct. 2016) PhD student: Mari-Liis Kauts, MSc (Jan. 2013 – Mar. 2017)
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Amelioration of sickle cell disease and ß-thalassemia: reactivation of g-globin gene expression.
- Name researcher:
- Dr T.D. van Dijk/Dr S. Philipsen/Prof F. Grosveld
- Duration:
- 4 years
- Year:
- 2010
- Amount granted:
- €408.500
- Project number:
- 1040
- Personnel:
- Dr Thamar Van Dijk, Dr J.N.J. (Sjaak) Philipsen (co-applicant), Prof Frank Grosveld (co-applicant), Dept. of Cell Biology, Erasmus MC PhD student: Ms Ileana Cantú, MSc (Oct. 2011 – Dec. 2015) PhD student: M. Mikropoulou, MSc (Jul. 2015 – Dec. 2015) Postdoc: Pavlos Fanis, PhD (Oct. 2011 – Jul. 2012) Technician: C.H.A.M. Gillemans (May 2015 – Dec. 2015)
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Dynamic fibrin clot formation: a haemostatic process involving multiple blood components and a possible surrogate end point for transfusion.
- Name researcher:
- Prof J.W.M. Heemskerk/Dr J.M.E.M. Cosemans
- Duration:
- 4 years
- Year:
- 2010
- Amount granted:
- €256.000
- Project number:
- 1006
- Personnel:
- Prof Johan W. M. Heemskerk, Dept. of Biochemistry, CARIM, Maastricht University PhD student: Frauke Swieringa, MSc (Oct. 2011 – Mar. 2015)
-
Neutrophil killing: a reappraisal of granulocyte transfusions for patients with fungal infections.
- Name researcher:
- Prof T.W. Kuijpers
- Duration:
- 4 years
- Year:
- 2010
- Amount granted:
- €380.500
- Project number:
- 1019
- Personnel:
- Prof Taco W. Kuijpers, Dept. of Pediatrics, Academic Medical Center, Amsterdam PhD student: Roel Gazendam, MSc (Mar. 2011 – Dec. 2015) Technician: Paul Verkuijlen (Jan. 2012 – Dec. 2013)
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Role of the microtubule network in the generation and expansion of the first hematopoietic stem cells.
- Name researcher:
- Dr. ir. N. Galjart/Dr C. Robin
- Duration:
- 4 years
- Year:
- 2010
- Amount granted:
- €388.000
- Project number:
- 1025
- Personnel:
- Dr ir Niels Galjart, Dept. of Cell Biology & Genetics, Erasmus MC, Rotterdam and Dr Catherine Robin (co-applicant), Hubrecht Institute, Utrecht Postdoc investigator: Umut Akinci Corbacioglu, PhD (Aug. 2011 – Dec. 2014) PhD student: Thomas Clapes, MSc (Dec. 2010 – Dec. 2014) Scientist: Sreya Basu (Oct. 2014 – Dec. 2014)
-
T cell modulation of hematopoiesis.
- Name researcher:
- Dr M.A. Nolte
- Duration:
- 4 years
- Year:
- 2010
- Amount granted:
- €560.000
- Project number:
- 1014F
- Personnel:
- Dr Martijn A. Nolte, Dept. of Hematopoiesis, Adaptive Immunity Lab, Sanquin Research, Amsterdam Postdoc: Maria Fernanda Pascutti, PhD (Oct. 2012 – May 2016) PhD student: Sulima Geerman, MSc (Nov. 2011 – Mar. 2016) Technician: Edith Slot (Jan. 2014 – Mar. 2015)
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The molecular basis of leukocyte transendothelial migration: from intracellular GEFs to intercellular gaps.
- Name researcher:
- Dr J.D. van Buul
- Duration:
- 4 years
- Year:
- 2010
- Amount granted:
- €560.000
- Project number:
- 1028F
- Personnel:
- Dr Jaap D. van Buul, Dept. of Molecular Cell Biology, Sanquin Research, Amsterdam PhD student: Niels Heemskerk, Msc (Sept. 2011 – Sept. 2015) PhD student: Anna E. Daniel, MSc (Sept. 2011 – Sept. 2015)
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A novel concept in leukocyte transendothelial migration: regulation of endothelial ICAM-1 function through inside-out signaling.
- Name researcher:
- Dr P.L. Hordijk
- Duration:
- 3 years
- Year:
- 2009
- Amount granted:
- €406.800
- Project number:
- 0903
-
Improving the potency of cytotoxic lymphocytes for adoptive therapy.
- Name researcher:
- Prof R.A.W. van Lier
- Duration:
- 3 years
- Year:
- 2009
- Amount granted:
- €145.350
- Project number:
- 0929
-
iPS cell technology for treatment of blood diseases: RAG1-Severe Combined Immunodeficiency.
- Name researcher:
- Dr H.M.M. Mikkers
- Duration:
- 4 years
- Year:
- 2009
- Amount granted:
- €379.800
- Project number:
- 0911
-
The impact of cholesterol metabolism on megakaryopoiesis and platelet production.
- Name researcher:
- Dr S. Korporaal
- Duration:
- 4 years
- Year:
- 2009
- Amount granted:
- €560.000
- Project number:
- 0912F
- Personnel:
- Dr Suzanne J.A. Korporaal, Dept. of Clinical Chemistry and Haematology, University Medical Center Utrecht and Prof Miranda van Eck, Division Biopharmaceutics, LACDR Postdoc: Suzanne J.A. Korporaal PhD (Jan. 2011 – Nov. 2015) PhD student: Marti Boss, MSc (Oct. 2010 – Jan. 2011) PhD student: Marco van der Stoep, MSc (Mar. 2012 – Mar. 2016)
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The role of γδT -cells in controlling relapse of hematopoietic malignancies and infections after allogeneic stem cell transplantation: Guiding to a new concept of T-cell based immunotherapies?
- Name researcher:
- Dr J. Kuball
- Duration:
- 4 years
- Year:
- 2009
- Amount granted:
- €246.250
- Project number:
- 0902
-
Variation in the FCGR2B and FCGR2C genes affect IgG-dependent platelet clearance during transfusion refractoriness.
- Name researcher:
- Prof T.W. Kuijpers
- Duration:
- 4 years
- Year:
- 2009
- Amount granted:
- €372.350
- Project number:
- 0916
-
Well Being of Obstetric Patients on Minimal Blood Transfusions (WOMB)
- Name researcher:
- Dr J.J. Duvekot
- Duration:
- 3 years
- Year:
- 2009
- Amount granted:
- €189.450
- Project number:
- 0904
-
A role for platelet glycoprotein Ib as a death receptor?
- Name researcher:
- Prof J.W.N. Akkerman
- Duration:
- 4 years
- Year:
- 2008
- Amount granted:
- €257.500
- Project number:
- 0807
-
Activation and inhibition of Factor VII-activating protease.
- Name researcher:
- Dr S. Zeerleder
- Duration:
- 4 years
- Year:
- 2008
- Amount granted:
- €390.300
- Project number:
- 0817
-
Delineating apoptosis pathways in normal and pathological erythropoiesis.
- Name researcher:
- Dr E. Eldering
- Duration:
- 3 years
- Year:
- 2008
- Amount granted:
- €330.900
- Project number:
- 0831
-
Genome Wide Association Study (GWAS) to identify genetic risk factors for blood group alloimmunisation.
- Name researcher:
- Prof C.E. van der Schoot/Prof W.H. Ouwehand/Prof A. Brand
- Duration:
- 3 years
- Year:
- 2008
- Amount granted:
- €346.500
- Project number:
- 0820
- Personnel:
- Prof C. Ellen van der Schoot, Dept. of Experimental Immunohematology, Sanquin, Amsterdam, co-applicants: Prof Willem H. Ouwehand, Dept. of Medicine, Cambridge, United Kingdom and Prof Anneke Brand, Transfusion Medicine, LUMC, Leiden Postdoc investigator: Dr Barbera Veldhuisen (Jan. 2010 – Nov. 2014) Senior technician: Onno Verhagen (Mar. 2012 – Dec. 2014)
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Graft versus Host disease by TCR-engineered T cells: mechanisms and means for prevention.
- Name researcher:
- Dr T.N.M. Schumacher
- Duration:
- 3 years
- Year:
- 2008
- Amount granted:
- €322.000
- Project number:
- 0804
-
Immunoglobulins: missing link in the development of human Th17 cells?
- Name researcher:
- Prof M.L. Kapsenberg/Dr S.M. van Ham/Dr E.C. de Jong
- Duration:
- 3 years
- Year:
- 2008
- Amount granted:
- €377.900
- Project number:
- 0816
-
Immunological dysbalance in childhood idiopathic thrombocytopenic purpura.
- Name researcher:
- Dr M. de Haas/Dr M. Bruin
- Duration:
- 4 years
- Year:
- 2008
- Amount granted:
- €390.300
- Project number:
- 0824
-
Leukocyte dynamics in healthy and stem-cell transplanted individuals.
- Name researcher:
- Dr J.A.M. Borghans/Dr K.Tesselaar
- Duration:
- 4 years
- Year:
- 2008
- Amount granted:
- €252.700
- Project number:
- 0812
-
Modulation of release of Weibel-Palade bodies from endothelial cells by small GTP- binding proteins.
- Name researcher:
- Dr J. Voorberg
- Duration:
- 4 years
- Year:
- 2008
- Amount granted:
- €390.300
- Project number:
- 0819
-
Control of lymphocyte polarity and chemotaxis.
- Name researcher:
- Dr P.L. Hordijk
- Duration:
- 4 years
- Year:
- 2007
- Amount granted:
- €399.700
- Project number:
- 0731
-
Improvement of the long-term function of transplanted hematopoietic stem cells.
- Name researcher:
- Dr R. van Os/Prof G. de Haan
- Duration:
- 3 years
- Year:
- 2007
- Amount granted:
- €229.500
- Project number:
- 0702